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Pfizer MAbs Monoclonal Antibody Small-Scale Facility - Engineering & Procurement

Executive Summary
Fluor provided a study, engineering and procurement services for Pfizer's Small-Scale MAbs Facility in Shanbally, Ireland.
Client's Challenge
Pfizer's MAbs SSF is a Phase III clinical trial and initial product launch facility to manufacture, purify, formulate and bulk fill mammalian cell culture-derived protein. The design of the facility provides for maximum flexibility, using disposable bag technology.
The facility produces an unspecified generic cell culture-derived protein for clinical testing and product launch.
Fluor's Solution
We performed a study and provided conceptual, preliminary and detailed engineering design, as well as procurement services for Pfizer's facility.
The Fluor team implemented value engineering on the project, and Pfizer accepted ideas totaling $4.6 million in savings, a 2.3% reduction in total installed cost.
Conclusion
We completed the project in 2008.
Pfizer was awarded the ISPE Facility of the Year Award for Sustainability in 2010.