Protein Design Labs Inc.
Brooklyn Park, MN, U.S.

Commercial-Scale Biotechnology Manufacturing Facility

Fluor was chosen by Protein Design Labs Inc. (PDL) to deliver a new biotech manufacturing facility in Brooklyn Park, Minnesota. Fluor provided front-end engineering, detailed design, procurement, automation, commissioning and validation for the project.

The large-scale facility produced antibody-based therapeutic drugs to treat autoimmune diseases, inflammatory conditions and certain forms of cancer. The development included a current good manufacturing practices (cGMP) facility with an attached warehouse and shipping facility and central utilities area, as well as a laboratory and administration building.

Client's Challenge

Protein Design Labs is a leader in the development of humanized antibodies to prevent or treat various disease conditions. This was the company's first large-scale commercial biotech manufacturing facility.

The greenfield project included 210,000 square feet of commercial manufacturing space, warehouse, laboratories, administrative areas, employee amenities and clean and plant utilities.

Fluor's Solution

Fluor provided the very latest cell culture technology expertise for the project with a low-cost design.

This important project award validated Fluor's demonstrated biotech expertise and strong execution platform.


The facility was completed in 2004.