Fluor is the Leading Provider of Engineering, Procurement, Construction Management and Validation (EPCMV) Services for the Biotechnology Industry.

Fluor designed and constructed the world's first biotech manufacturing facility for Genentech back in 1982. Since the market's inception, Fluor has designed or built more than 75 biotech facilities that produce more than three-fourths of today's biotech sales. Fluor has had unparalleled success in commercializing first-of-a-kind processes and scale‑up.

Product Types:

  • Adjuvants
  • Cellular therapies
  • Clotting factors/anticoagulants
  • Enzymes
  • Gene therapies
  • Growth factors
  • Insulin & hormones
  • Monoclonal antibodies (MAbs)
  • Oligonucleotides
  • Plasma fractionation
  • Plasma-derived products
  • Peptides
  • Vaccines

Technologies Expertise:

  • Biocontainment
  • Cleaning & bioburden control
  • Commissioning, qualification, & validation (CQV)
  • Continuous manufacturing
  • Hygienic system design
  • Process automation
  • Regulatory compliance
  • Single-use system design & integration
  • Start-up

Unit Operations Expertise:

  • Bio-inactivation
  • Bioreactors
  • Centrifugation
  • Chromatography:
    • Affinity
    • Ion exchange
    • Reverse phase HPLC
    • Size exclusion
  • CIP/SIP
  • Cleanroom design
  • Depth filtration
  • Fermentation
  • Isolation technology
  • Lyophilization
  • Packaging
  • Specialized utility systems:
    • Clean-in-place (CIP)
    • Steam-in-place (SIP)
    • USP purified water systems
    • Water-for-injection (WFI) systems
  • Sterile filling
  • Tangential flow filtration
  • Viral removal/inactivation
  • Vial and syringe filling

Fluor's clients include both new venture start-ups and fully integrated manufacturers. As a full-spectrum EPCMV provider, Fluor has extensive experience delivering FDA-licensed facilities for critical time-to-market launches.

Learn more about Fluor's life sciences project execution approach.