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Life Sciences Projects

Large-Scale Manufacturing Facility
Puerto Rico

Fluor is executing an integrated engineering, procurement, construction management, validation (EPCMV) project involving a large-scale biotech manufacturing facility in Puerto Rico to produce a human insulin product. This plant is the largest modular constructed biologics manufacturing facility in the world. Fluor's Greenville, South Carolina, and San Juan, Puerto Rico, offices, are working as a team in executing the design of this project. Construction and validation activities are being coordinated by Fluor's on-site team.

Highlights include:
  • Full scope of EPCMV services provided by Fluor
  • Logistically complex project involving the coordination of the trafficking logistics and construction of more than 600 modules from five module fabricators in four countries
  • First-of-a-kind modular large-scale manufacturing facility
  • Long-term relationships in Puerto Rico securing permits from known entities and reliable delivery from prequalified specialty subcontractors
  • Biologic production support systems and utilities
  • Laboratory areas
  • Successful, multiple-office execution

Bulk Manufacturing Facility
Ireland

Fluor provided program management, construction management, and design review services for a facility near Dublin, Ireland. The bulk manufacturing facility will produce active pharmaceutical ingredients for a range of health care treatments. This expansive greenfield project encompasses a 100-acre campus and is one of the largest bulk operations in the world.

Highlights of the project include:
  • Program management, design review services, construction management and validation/commissioning services provided by Fluor
  • Fluor executed 2.7 million safe work hours without a lost-time incident
  • Received national recognition for safety achievement from Irish Minister of Labor, Tom Kitt
  • Greenfield facility
  • API production
  • Administration/Office space
  • Laboratory facilities
  • Successful and cost-effective worksharing between offices

Large-Scale Cell Culture Manufacturing Facility
Rhode Island

Fluor provided construction management services on this large-scale cell culture manufacturing facility. Fluor was asked to replace the original construction manager in 2002. The BioNext project includes the completion of construction and process work on a campus that will provide the production capabilities to supply product to thousands of patients worldwide.

Highlights include:
  • Construction management services provided by Fluor
  • Biologic product manufacturing facility
  • Successful negotiation of a Project Labor Agreement
  • Successful worksharing between Fluor offices
  • Accelerated the project to be completed 16 weeks ahead of the baseline plan
  • Achieved over 1 million safe work hours to date

Vaccines Manufacturing
North Carolina

Fluor has been actively involved in North Carolina and Research Triangle Park projects for over 15 years, with multiple projects executed at this client's North Carolina campus since 1996. Successful execution of these projects has resulted in numerous safety awards for Fluor from the State of North Carolina.

Highlights of these projects include:
  • Full scope of project services provided on multiple projects
  • Long-term, ongoing relationship on same site
  • Vaccines/biological manufacturing facilities
  • Selected modular construction components
  • Greenfield sites
  • Analytical development and testing laboratories
  • Successful management of local, prequalified subcontractors
  • Successful worksharing between Fluor offices meeting all schedule goals