Fluor is the leading provider of engineering, procurement, construction and validation (EPCV) services for the pharmaceutical industry.

Fluor has designed and built various types of bulk pharmaceutical facilities, employing batch, semi-continuous and continuous operations including:

- Pilot plant facilities
- Full multipurpose commercial-scale facilities (using modular reactor suites, flexible equipment arrangement to allow easy clean-out and quick switching of piping and controls)
- High-containment facilities (for handling hazardous chemicals such as chlorine, phosgene, hydrogen cyanide, ammonia, methylene chloride and hydrofluoric acid)
- Bulk Active Pharmaceutical Ingredient (API)
- Solids (Effervescent dosages, solid oral dosage forms such as Tablets, Capsules, and Powders)
- Liquids (Ophthalmic solutions, Inhalers)

Fluor's experienced teams ensure optimization of Client's critical process steps.

Fluor's experienced teams ensure optimization of Client's critical process steps involving reaction, purification, extraction, crystallization, separation/filtration, and drying. Our technical expertise in process design provides innovative solutions to address batch feed systems for solids or liquids; reactor design; product purification; extraction and computer resources. Fluor maintains steady-state process simulators that evaluate continuous processes such as solvent recovery systems that employ high vacuum distillation.

Since bulk pharmaceutical plants are subject to CGMP and regulatory requirements, Fluor provides a project organization and execution approach that ensures FDA, EU, and SFDA regulations are met as required and that completed facilities are rapidly commissioned and qualified.

Project experience includes pilot plants, greenfield, upgrades, retrofits, expansions and decommissioning projects.

Learn more about Fluor's project execution approach.