Fluor is the leading provider of engineering, procurement, construction and validation (EPCV) services for the Biotechnology industry.

Fluor designed and constructed the world's first biotech manufacturing facility for Genentech back in 1982. Since the market's inception, Fluor has designed or built more than 75 biotech facilities that produce more than three-fourths of today's biotech sales. We have unparalleled success in commercializing first-of-a-kind processes and scale-up.

Technologies Expertise:

  • Mammalian cell culture
  • Microbial and industrial fermentation
  • Vaccines
  • Monoclonal antibodies
  • Peptides
  • Oligonucleotides
  • Plasma processing / Fractionation
  • Biotherapeutic
  • Gene therapy
  • Specialized utility systems:
    • Clean-in-place (CIP)
    • Steam-in-place (SIP)
    • USP purified water systems
    • Water-for-injection (WFI) systems
    • DI
  • Process automation
  • Biocontainment
  • Isolation technology
  • Clean room design
  • Commissioning & Qualification
  • Regulatory compliance
  • Start-up

Unit Operations Expertise:

  • Fermentation
  • Tangential flow filtration
  • Centrifugation
  • Chromatography:
    • Ion exchange
    • Affinity
    • Reverse phase HPLC
    • Size exclusion
  • Vial and syringe filling
  • Sterile filling
  • Packaging
  • Lyophilization
  • Bio-inactivation
  • CIP/SIP

Fluor partners with Clients from new venture start-ups to fully integrated manufacturers. As a full-spectrum EPCV provider, Fluor has extensive experience delivering FDA-licensed facilities for critical time-to-market launches.

Learn more about Fluor's project execution approach.

Extensive experience delivering FDA-licensed facilities for critical time-to-market launches